Management of Herpesvirus Infections in Hematopoietic Cell Transplant Recipients

Following primary infection, herpesviruses establish latency in infected individuals the host cells and may reactivate upon external stimuli during periods of immunosuppression. The objective this paper was to present current strategies on preventive therapeutic management infections with recipients hematopoietic cell transplantation. Strategies antiviral include prophylaxis, pre-emptive treatment targeted treatment. Empirical therapy is not used strategies. Prophylaxis can be done at universal (preventive strategy) specific level. Universal prophylaxis includes non-pharmacologic methods prevention infection or reactivation. Risk-adapted use antivirals cellular other order prevent high-risk groups. Pre-emptive means approaches asymptomatic detected by a screening assay. Targeted established viral end-organ infections. following sections refer strategies, respectively, against CMV, EBV, HSV, VZV, HHV-6, HHV-7, HHV-8 after allogeneic